Gene information
Official symbol F3
Official full name coagulation factor III, tissue factor
Gene type protein-coding gene
Chromosome1p21.3
Alias symbolCD142; TF
Gene familyCD molecules
Resources
Entrez Gene 2152
HGNC HGNC:3541
Ensembl ENSG00000117525
Vega OTTHUMG00000010716
UCSC uc001dqr.4
GO terms: 72 records
GO Description Category LogP Number of genes Detail
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0001936 regulation of endothelial cell proliferation GO Biological Processes -54.5504306 75 More
GO:0001938 positive regulation of endothelial cell proliferation GO Biological Processes -32.0012114 45 More
GO:0002020 protease binding GO Molecular Functions -28.8254555 31 More
GO:0002526 acute inflammatory response GO Biological Processes -34.5980034 29 More
GO:0004175 endopeptidase activity GO Molecular Functions -25.2809598 44 More
GO:0004252 serine-type endopeptidase activity GO Molecular Functions -24.0834770 30 More
GO:0004896 cytokine receptor activity GO Molecular Functions -9.30297759 21 More
GO:0005543 phospholipid binding GO Molecular Functions -6.61792344 45 More
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -5.45408545 14 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0007596 blood coagulation GO Biological Processes -44.7281461 45 More
GO:0007599 hemostasis GO Biological Processes -44.1075001 45 More
GO:0008233 peptidase activity GO Molecular Functions -21.0463733 46 More
GO:0008236 serine-type peptidase activity GO Molecular Functions -23.9716175 31 More
GO:0008289 lipid binding GO Molecular Functions -15.8223476 88 More
GO:0009611 response to wounding GO Biological Processes -63.1714102 77 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0010950 positive regulation of endopeptidase activity GO Biological Processes -13.2452311 34 More
GO:0010952 positive regulation of peptidase activity GO Biological Processes -14.1524623 37 More
GO:0016485 protein processing GO Biological Processes -23.0561441 30 More
GO:0017171 serine hydrolase activity GO Molecular Functions -24.8900503 32 More
GO:0019221 cytokine-mediated signaling pathway GO Biological Processes -27.5840932 43 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0030193 regulation of blood coagulation GO Biological Processes -37.6853179 30 More
GO:0030194 positive regulation of blood coagulation GO Biological Processes -18.9359595 14 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031233 intrinsic component of external side of plasma membrane GO Cellular Components -2.55598907 3 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032677 regulation of interleukin-8 production GO Biological Processes -20.0046302 33 More
GO:0032757 positive regulation of interleukin-8 production GO Biological Processes -14.6396218 15 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042060 wound healing GO Biological Processes -56.2139708 65 More
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -11.0338596 16 More
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -14.7594418 39 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0045766 positive regulation of angiogenesis GO Biological Processes -39.3444092 63 More
GO:0045862 positive regulation of proteolysis GO Biological Processes -17.3242033 33 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050679 positive regulation of epithelial cell proliferation GO Biological Processes -31.4834672 59 More
GO:0050817 coagulation GO Biological Processes -44.4773041 45 More
GO:0050818 regulation of coagulation GO Biological Processes -40.0839917 32 More
GO:0050820 positive regulation of coagulation GO Biological Processes -18.6547980 14 More
GO:0050878 regulation of body fluid levels GO Biological Processes -57.9546976 69 More
GO:0050920 regulation of chemotaxis GO Biological Processes -36.3269885 43 More
GO:0050921 positive regulation of chemotaxis GO Biological Processes -35.4880405 36 More
GO:0050926 regulation of positive chemotaxis GO Biological Processes -15.5115450 16 More
GO:0050927 positive regulation of positive chemotaxis GO Biological Processes -14.3403642 15 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0051604 protein maturation GO Biological Processes -20.0856790 31 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051897 positive regulation of protein kinase B signaling GO Biological Processes -23.7578366 39 More
GO:0052547 regulation of peptidase activity GO Biological Processes -35.5643317 55 More
GO:0052548 regulation of endopeptidase activity GO Biological Processes -34.9486589 53 More
GO:0061041 regulation of wound healing GO Biological Processes -35.8633788 36 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:0090303 positive regulation of wound healing GO Biological Processes -15.9447313 16 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0140375 immune receptor activity GO Molecular Functions -8.53513203 25 More
GO:1900046 regulation of hemostasis GO Biological Processes -39.0044157 31 More
GO:1900048 positive regulation of hemostasis GO Biological Processes -18.9359595 14 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1903034 regulation of response to wounding GO Biological Processes -34.9293555 38 More
GO:1903036 positive regulation of response to wounding GO Biological Processes -14.4451296 16 More
GO:1904018 positive regulation of vasculature development GO Biological Processes -39.3444092 63 More
GO:2000116 regulation of cysteine-type endopeptidase activity GO Biological Processes -14.4496812 41 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2001056 positive regulation of cysteine-type endopeptidase activity GO Biological Processes -11.1582582 17 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04610 Complement and coagulation cascades KEGG Pathway -50.1154932 39 More
hsa04933 AGE-RAGE signaling pathway in diabetic complications KEGG Pathway -25.8646207 26 More
Drug-Gene interaction
view
Related drugs: 1 record
Drug name Interaction type Source PMID View
simvastatin PharmGKB 19027114 view
Related studies: 12 records
Molecular factor Omics type Application Objective MI type Reference
F3 transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Wang R et al. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011
NM_001993.5:c.-603A>G genomics myocardial infarction[diagnosis] myocardial infarction Ott I et al. Atherosclerosis. 2004
tissue factor proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Soejima H et al. Am J Cardiol. 1996
tissue factor proteomics enalapril[treatment (pharmacotherapy)] acute myocardial infarction Soejima H et al. Am J Cardiol. 1996
tissue factor proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Suefuji H et al. Am Heart J. 1997
tissue factor proteomics enalapril[treatment (pharmacotherapy)] acute ST elevation myocardial infarction Soejima H et al. J Am Coll Cardiol. 1999
tissue factor proteomics adverse events[prognosis (bad)] acute myocardial infarction Seljeflot I et al. Thromb Res. 2003
tissue factor proteomics no-reflow phenomenon[prognosis (bad)] acute myocardial infarction Xu P et al. Zhonghua Xin Xue Guan Bing Za Zhi. 2008
tissue factor proteomics cardiovascular death[prognosis (bad)] acute myocardial infarction Steppich BA et al. Thromb J. 2009
tissue factor proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Wang R et al. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011
tissue factor proteomics clopidogrel[treatment (pharmacotherapy)] acute myocardial infarction Boinska J et al. Platelets. 2019
tissue factor proteomics left ventricular thrombus[prognosis (bad)] acute myocardial infarction Solheim S et al. Thromb J. 2013
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